Proton Pump Inhibitors Drugs Uses and Side Effects


PPIs or proton pump inhibitors are the drugs that inhibits the proton pump channels which helps in decrease acid production. Proton pump inhibitors blocks the enzymes present on the wall of stomach, which is responsible for acid generation which forms ulcers.


Why we use proton pump inhibitors?

We need to use proton pump inhibitors when we face any of the problem mentioned below:
  • Ulcer associated by Non-steroidal anti-inflammatory drugs.
  • Esophageal ulcer
  • Stomach ulcer
  • Duodenal ulcer
  • Zollinger Ellison syndrome disease
  • Gastroesophageal reflux disease
Common side effects of proton pump inhibitors
Headache, constipation, vomiting, nausea, diarrhea, fever, lower abdominal pain, rashes.

Uncommon side effects of proton pump inhibitors
Reduction in kidney function, Reduction in liver function, Inflammation in pancreas, Serious allergic reactions, toxic epidermal necrolysis etc.

Examples of Proton pump inhibitors
  • Dexlansoprazole
  • Esomeprazole
  • Pantoprazole
  • Rabeprazole
  • Lansoprazole
  • Omeprazole
These proton pump inhibitors are available in different dosage forms like Tablet form, Capsule form, Injection form.

You can get all these dosage forms of proton pump inhibitors at Affy Group, they are the generic manufacturer, contract manufacturer, third party manufacturer as well as export manufacturer of general tablets in India, as well as capsules and lyophilized injections also. They have wide list of proton pump inhibitors like esomeprazole, pantoprazole, rabeprazole, omeprazole.

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