How Does Anticancer Drugs Treat Cancer?
In present scenario the number of cancer
patients is much more as compared to the data of ten years back. Many peoples
are not aware that in actual what are anticancer medicines and how they work?
Before starting any cancer treatment
patients should know about these terms:
Anticancer medicines are the group of
medicines indicated for the treatment of different types of cancers.
Action of Anticancer Medicines
- Drugs belongs to alkylating agents like nitrosoureas, triazines etc interfares in linkage of DNA.
- Antracyclines drugs like daunorubicin, doxorubicin etc damage the DNA cells present in cancer cells.
- Antimetabolites drugs like capecitabine, methotrexate etc affects the synthesis of DNA in cancerous cells.
- Aromatase inhibitors drugs like letrozole, anastrozole works by blocking of aromatase enzyme.
- HDAC (Histone deacetylase)inhibitors drugs like belinostat, romidepsin etc inhibits the DNA repairment.
- Mtor inhibitor drugs like temsirolimus etc works by blocking of growth regulating enzymes
- PARP inhibitors drugs like olaparib niraparib etc helps in mutations in DNA repairment
- Retinoids drugs like bexarotene etc involves in inhibition of growth of tumor.
- Kinase inhibitors drugs like imatinib, nilotinib involves in blockage of kinase enzymes.
- Topoisomerase inhibitors drugs like topotecan involves in blockage of topoisomerase enzyme.
- Vinca alkaloids drugs like Vinblastine, Vincristine involves in inhibition of tubulin, main microtubules content of cell, results in death of cell.
Patients also face problems regarding
availability of anticancer tablets, capsules, Injection in their nearest
pharmacy. One of my known also getting the same problem and then someone
suggest him the name of Affy group, they are Anticancer Injection manufacturerin India having medicines like Doxorubicin Hydrochloride Injection, Bleomycin
Injection, Zoledronic acid injection etc.
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